News Release

OpGen Reports First Quarter 2020 Financial Results and Provides Business Update

05.07.20
  • Total Revenue for Q1 2020 was approximately $617,000 (excluding Curetis Revenue)
  • Curetis and Ares revenue was approximately $900,000 for the first quarter generating a pro forma combined unaudited revenue of over $1.5 million
  • Balance sheet strengthened significantly with $13.9 million cash raised in Q1 2020
  • OpGen and Curetis successfully completed business combination effective April 1, 2020
  • Multiple shipments of BGI SARS-CoV-2 rapid PCR kits completed by Curetis in Europe. Additional actions planned to address the global COVID-19 pandemic

Conference call to be held at 4:30 p.m. Eastern Time today

GAITHERSBURG, Md., May 07, 2020 (GLOBE NEWSWIRE) -- OpGen, Inc. (Nasdaq: OPGN, “OpGen”), a precision medicine company harnessing the power of molecular diagnostics and informatics to help combat infectious disease, reported today its stand-alone financial and operating results for the three months ended March 31, 2020 and provided a business update. Total OpGen revenue for the first quarter of 2020 was approximately $617,000 down from $1.0 million in the first quarter of 2019. Revenue from Curetis and Ares, OpGen’s wholly owned subsidiaries, was approximately $900,000 for the first quarter generating a pro-forma combined unaudited revenue of over $1.5 million. OpGen’s cash as of March 31, 2020 was approximately $11.5 million, up significantly from the $2.7 million as of December 31, 2019. This amount did not include the approximately $900,000 in cash held by Curetis and Ares at March 31, 2020.

Oliver Schacht, President and CEO of OpGen commented, “Despite the unprecedented global crisis situation with COVID-19, we are pleased with our first quarter results and remain confident in the strength of our 2020 pipeline. We acknowledge that this is an ever-changing situation and are prepared to mitigate any further potential impact that COVID-19 might have on our global operations. We would like to reassure you that as a company we are resilient and OpGen with its subsidiaries Curetis and Ares Genetics boasts a strong proprietary product portfolio that is extremely agile, flexible and has elements in place to rapidly identity, develop and create potential offerings needed to address future infectious disease outbreaks.”

Mr. Schacht continued, “We expect the CoV-2 rapid PCR test kit sales in Europe to continue contributing positively to our top-line revenue in Q2 of 2020. Since mid-March 2020, we sold approximately 15,000 CoV-2 tests into our distribution network. Additionally, we recently announced our collaboration with Sweden’s Karolinska Institutet to test COVID-19 pneumonia patients with Unyvero HPN panel for bacterial co-infections. Due to the nature of the CoV-2 virus, we believe it is crucial to be able to rapidly detect a comprehensive spectrum of bacterial and fungal pathogens and antibiotic resistance markers in lower respiratory tract specimens that  could be a critical factor in saving patients lives during the ongoing pandemic. The study has already started and we expect to see initial results in the coming weeks.”

First Quarter 2020 Financial Results of OpGen, Inc. Stand-alone

  • Total revenue for the first quarter of 2020 was approximately $617,000 down from $1.0 million in the first quarter of 2019. This decrease can be attributed to Acuitas AMR Gene Panel and Acuitas® Lighthouse revenue, which was approximately $254,000, while revenues from the company’s rapid FISH products decreased to $363,000. Curetis and Ares revenue was approximately $900,000 for the first quarter generating a pro forma combined unaudited revenue of over $1.5 million.
  • Operating expenses for the first quarter of 2020 were $4.6 million, compared with $4.8 million in the first quarter of 2019.
  • The net loss for the first quarter of 2020 was $3.9 million or $0.53 per share, compared with $3.9 million or $8.25 per share in the first quarter of 2019.

The Company also provided the following business updates that were achieved during the first quarter of 2020:

  • Successful closure of the business combination between OpGen and Curetis on April 1, 2020. At the closing, William E. Rhodes III, the former chairman of the Supervisory Board of Curetis N.V., was appointed chairman of the board of OpGen, and Oliver Schacht, Ph.D., the former Chief Executive Officer of Curetis N.V., was appointed the President and Chief Executive Officer of OpGen and to the board of directors;
  • The newly formed board of directors of OpGen now also includes Evan Jones, former Chairman and CEO of OpGen, Don Elsey, Mario Crovetto, and Prabhavathi Fernandes, PhD;
  • Announced the start of an investigator initiated collaboration with Karolinska Institutet, Sweden, to identify bacterial co-infections in patients admitted to the ICU for COVID-19 pneumonia using the Unyvero HPN panel;
  • OpGen significantly improved its working capital position in the first quarter of 2020 through $5.8 million of sales under the company’s ATM program and $8.1 million in proceeds from the exercise of warrants issued in the company’s public offering in October 2019;
  • Clinical trials were initiated during the first quarter of 2020 at nine participating sites for the Acuitas AMR Gene Panel (Urine) test. Testing and the trial have been suspended due to hospital actions to focus resources on the COVID-19 pandemic;
  • Acuitas Lighthouse® was utilized in a research study conducted by the Mayo Clinic to predict phenotypic resistance and antimicrobial susceptibility among clinical isolates, with findings published in Diagnostic Microbiology & Infectious Disease; and
  • Curetis, Ares Genetics, and BGI announced a partnership around BGI’s CoV-2 test kit commercialization in Europe; Curetis has begun selling the BGI CoV-2 product via its distribution network in EMEA during Q1 2020 and to date has sold over 15,000 tests into its distribution network.

Additional key business updates and strategic milestones include:

  • OpGen’ expects that its submission to the U.S. Food and Drug Administration (“FDA”) for clearance of the Acuitas® AMR Gene Panel (Isolates) for the detection of antimicrobial resistance genes in bacterial isolates is nearing completion. OpGen has responded, and is continuing to respond, to the FDA’s additional information requests and now anticipates approaching a clearance decision for the Acuitas® AMR Gene Panel for isolates. Exact timing is unknown as a result of the COVID-19 pandemic;
  • OpGen successfully achieved the last of the first year milestones in the groundbreaking collaboration with the New York State Department of Health and ILÚM Health Solutions, LLC, to develop a state-of-the-art research program to detect, track, and manage antimicrobial-resistant infections at healthcare institutions statewide. In response to the COVID-19 emergency in New York State, testing under the program has been put on hold by the Wadsworth Center and participating hospitals; however, the parties are currently engaged in active negotiations and discussions for a second year of the collaboration and expect to resume the project and expand it into its second year once the COVID-19 situation permits;
  • OpGen’s subsidiary Ares Genetics in April announced that a study on the feasibility and potential of antibiotic susceptibility testing and bacterial pathogen identification using next-generation sequencing (NGS) has been pre-published in the Journal of Clinical Microbiology. The study was performed by Ares Genetics GmbH and Curetis GmbH, and scientists at the Max Perutz Labs (Austria), a joint venture of the University of Vienna and the Medical University of Vienna, and the Mayo Clinic (Rochester, MN, U.S.A.); and
  • Curetis and Quaphaco entered into an exclusive three-year distribution partnership for the Unyvero product line in Vietnam; the contract includes minimum commitments by Quaphaco totaling approximately $ 2.1 million over the initial three-year term.

Mr. Schacht continued, “We have a strong pipeline heading into the second quarter of 2020 despite the unique market challenges presented at this time. With the anticipated near term FDA clearance decision and subsequent launch of our Acuitas AMR Gene Panel product for isolate and the exciting combination of the Acuitas Lighthouse® database with the ARESdb, our strong, proprietary product pipeline attests to our ability to deliver premier AI-powered bioinformatics solutions and diagnostic products. We are especially excited about an upcoming major milestone in the Ares collaboration with its strategic R&D collaboration partner, a leading global IVD corporation, where completion of the R&D phase is expected for the third quarter this year. The IVD corporate partner has pre-funded an option which upon exercise would then grant it 90 days of exclusive negotiations with Ares regarding a potential future partnering and licensing deal.”

Conference Call Information

OpGen’s management will host a conference call today, May 7 at 4:30 p.m. ET to discuss first quarter financial results and other business activities, as well as answer questions. Dial-in information is below:

Dial-in Information
U.S. Dial-in Number: +1 (844) 420-8185
International Dial-in Number: +1 (216) 562-0481
Webcast: https://edge.media-server.com/mmc/p/iggnmjim
Conference ID: 8595009

Following the conclusion of the conference call, a replay will be available through May 14, 2020. The live, listen-only webcast of the conference call may also be accessed by visiting the Investors section of the Company’s website at www.opgen.com. A replay of the webcast will be available following the conclusion of the call and will be archived on the Company’s website for 90 days. Replay access information is below:

Replay Information
U.S. Dial-in Number: +1 (855) 859-2056
International Dial-in Number: +1 (404) 537-3406
Conference ID: 8595009

About OpGen, Inc.

OpGen, Inc. (Gaithersburg, MD, USA) is a precision medicine company harnessing the power of molecular diagnostics and bioinformatics to help combat infectious disease. Along with subsidiaries, Curetis GmbH and Ares Genetics GmbH, we are developing and commercializing molecular microbiology solutions helping to guide clinicians with more rapid and actionable information about life threatening infections to improve patient outcomes, and decrease the spread of infections caused by multidrug-resistant microorganisms, or MDROs. OpGen’s product portfolio includes Unyvero, Acuitas AMR Gene Panel and Acuitas Lighthouse, and the ARES Technology Platform including ARESdb, using NGS technology and AI-powered bioinformatics solutions for antibiotic response prediction.

For more information, please visit www.opgen.com.

Forward-Looking Statements

This press release includes statements regarding OpGen’s first quarter 2020 results, the integration of Opgen with its acquired subsidiaries, Curetis GmbH and Ares Genetics GmbH, the current business and strategic initiatives of OpGen, and the impact of COVID-19 on the company and general market conditions. These statements and other statements regarding OpGen’s future plans and goals constitute "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and are intended to qualify for the safe harbor from liability established by the Private Securities Litigation Reform Act of 1995. Such statements are subject to risks and uncertainties that are often difficult to predict, are beyond our control, and which may cause results to differ materially from expectations. Factors that could cause our results to differ materially from those described include, but are not limited to, our ability to successfully, timely and cost-effectively develop, seek and obtain regulatory clearance for and commercialize our product and services offerings, the rate of adoption of our products and services by hospitals and other healthcare providers, the realization of expected benefits of our business combination transaction with Curetis GmbH, the success of our commercialization efforts, the impact of COVID-19 on the Company’s operations, financial results, and commercialization efforts as well as on capital markets and general economic conditions, the effect on our business of existing and new regulatory requirements, and other economic and competitive factors. For a discussion of the most significant risks and uncertainties associated with OpGen's business, please review our filings with the Securities and Exchange Commission. You are cautioned not to place undue reliance on these forward-looking statements, which are based on our expectations as of the date of this press release and speak only as of the date of this press release. We undertake no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events or otherwise.

OpGen:
Oliver Schacht
President and CEO
InvestorRelations@opgen.com

OpGen Press Contact:
Matthew Bretzius 
FischTank Marketing and PR
matt@fischtankpr.com

OpGen Investor Contact:
Joe Green
Edison Group 
jgreen@edisongroup.com


OpGen, Inc.
Consolidated Balance Sheets
(unaudited)
         
    March 31, 2020   December 31, 2019
Assets        
Current assets        
Cash and cash equivalents   $ 11,469,455     $ 2,708,223  
Accounts receivable, net     165,931       567,811  
Inventory, net     436,683       473,030  
Note receivable     4,808,712       2,521,479  
Prepaid expenses and other current assets     264,013       396,760  
Total current assets       17,144,794         6,667,303  
Property and equipment, net     102,579       130,759  
Finance lease right-of-use assets, net     826,243       958,590  
Operating lease right-of-use assets     885,882       1,043,537  
Goodwill     600,814       600,814  
Intangible assets, net           817,550  
Other noncurrent assets     203,212       203,271  
Total assets   $   19,763,524     $   10,421,824  
Liabilities and Stockholders’ Equity        
Current liabilities        
Accounts payable   $ 1,054,261     $ 1,056,035  
Accrued compensation and benefits     988,291       855,994  
Accrued liabilities     1,047,019       1,046,661  
Deferred revenue     9,808       9,808  
Short-term notes payable     348,494       373,599  
Short-term finance lease liabilities     517,042       579,030  
Short-term operating lease liabilities     947,610       1,017,414  
Total current liabilities       4,912,525         4,938,541  
Note payable     163,401       329,456  
Long-term finance lease liabilities     212,798       313,263  
Long-term operating lease liabilities     392,106       547,225  
Total liabilities       5,680,830         6,128,485  
Stockholders' equity        
Preferred stock, $0.01 par value; 10,000,000 shares authorized; none issued and
  outstanding at March 31, 2020 and December 31, 2019, respectively
           
Common stock, $0.01 par value; 50,000,000 shares authorized; 12,468,214 and
  5,582,280 shares issued and outstanding at March 31, 2020 and
  December 31, 2019, respectively
    124,682       55,823  
Additional paid-in capital     192,410,127       178,779,814  
Accumulated deficit     (178,474,277 )     (174,524,983 )
Accumulated other comprehensive income/(loss)     22,162       (17,315 )
Total stockholders’ equity       14,082,694         4,293,339  
Total liabilities and stockholders’ equity   $   19,763,524     $   10,421,824  


OpGen, Inc.
Consolidated Statements of Operations and Comprehensive Loss
(unaudited)
    Three Months Ended March 31,
      2020       2019  
Revenue        
Product sales   $ 366,933     $ 520,177  
Collaboration revenue     250,000       500,000  
Total revenue     616,933       1,020,177  
Operating expenses        
Cost of products sold     276,554       220,702  
Cost of services     137,666       144,482  
Research and development     1,217,556       1,776,382  
General and administrative     1,701,448       1,747,585  
Sales and marketing     282,277       372,233  
Transaction costs     245,322        
Impairment of intangible assets     750,596        
Impairment of right-of-use asset           520,759  
Total operating expenses     4,611,419       4,782,143  
Operating loss     (3,994,486 )     (3,761,966 )
Other income (expense)        
Interest and other income (expense)     87,335       (24,422 )
Interest expense     (38,267 )     (56,444 )
Foreign currency transaction losses     (3,876 )     (10,351 )
Change in fair value of derivative financial instruments           67  
Total other income (expense)     45,192       (91,150 )
Loss before income taxes     (3,949,294 )     (3,853,116 )
Provision for income taxes            
Net loss   $ (3,949,294 )   $ (3,853,116 )
         
Net loss per common share - basic and diluted   $ (0.53 )   $ (8.25 )
Weighted average shares outstanding - basic and diluted     7,393,232       467,286  
Net loss   $ (3,949,294 )   $ (3,853,116 )
Other comprehensive income - foreign currency translation     39,477       2,826  
Comprehensive loss   $ (3,909,817 )   $ (3,850,290 )

OpGen.jpg

Source: OpGen, Inc.